Fig. 3

X-ray irradiation down-regulates DNMT1, DNMT3b and MeCP2 in lung cancer cells. a Western blot demonstrates the effect of X-ray irradiation on the expression of DNMTs and MeCP2. DNMT1, DNMT3b and MeCP2 were down-regulated significantly in irradiated LK cells compared with non-irradiated cells (P < 0.05), but not obvious change of DNMT3a expression was observed; b The histogram of A; c Decreased expression of DNMT1, DNMT3b and MeCP2 after X-ray irradiation in SPC cells (P < 0.05); d The histogram of C. * P < 0.05