Fig. 1
Characterization of 5-Fu-resistant HCC cells: a to c Bel-7402 or Bel/5-Fu cells were treated by different concentrations of 5-fluorouracil (0 to 104 μM), oxaliplatin (0 to 103 μM), or doxorubicin (0 to 102 μM) for 24 h, respectively. The cell viability was determined in triplicate, and the IC50s were calculated. d and e The intracellular ROS levels were determined in triplicate (the H2O2-treated Bel-7402 cells were used as a positive control; Bars = 250 μm)