Fig. 3

14–3-3ζ promotes cell proliferation in vitro and tumor growth in vivo (a-c) Cell proliferation was measured by the CCK-8 assay. ***P < 0.001 compared with corresponding NC or Vector. d-f Cell proliferation was examined by a colony formation assay, and relative clone number was used for statistic analysis. Data represent the mean ± SD of three independent experiments. P-values were calculated using the Student’s t-test. g-i 14–3-3ζ knockdown suppresses HCC tumor growth in vivo. g: Photos of the xenograft tumors; h Tumor volume; i Tumor weights. ***P < 0.001