Fig. 8From: Activation of dynamin-related protein 1 - dependent mitochondria fragmentation and suppression of osteosarcoma by cryptotanshinoneAntitumor ability of CPT was Drp1 dependent. Efficacy of CPT in combination with Mdivi-1 in xenograft model bearing 143B cells. 143B cells were inoculated subcutaneously in NOD/SCID mice, tumors were allowed to form, and then mice were treated with CPT combined with or without Mdivi-1 (0.5 mg/mice). Representative tumor images are shown here. Tumor volumes and tumor weight were examined throughout the experiment. (n = 3 mice/group; *P < 0.05). Bar represents 1 cmBack to article page