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Fig. 8 | Journal of Experimental & Clinical Cancer Research

Fig. 8

From: Activation of dynamin-related protein 1 - dependent mitochondria fragmentation and suppression of osteosarcoma by cryptotanshinone

Fig. 8

Antitumor ability of CPT was Drp1 dependent. Efficacy of CPT in combination with Mdivi-1 in xenograft model bearing 143B cells. 143B cells were inoculated subcutaneously in NOD/SCID mice, tumors were allowed to form, and then mice were treated with CPT combined with or without Mdivi-1 (0.5 mg/mice). Representative tumor images are shown here. Tumor volumes and tumor weight were examined throughout the experiment. (n = 3 mice/group; *P < 0.05). Bar represents 1 cm

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