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Fig. 8 | Journal of Experimental & Clinical Cancer Research

Fig. 8

From: CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p

Fig. 8

miR-133a-3p was negatively associated with the expression of RhoA in human CRC specimens. a-c Statistical analysis of the mRNA level of CXCR4, RhoA and miR-133a-3p in 22 pairs of human colon tissues and adjacent normal colon tissue. d The expression and location of CXCR4, RhoA and CD68 were analyzed by IHC assay in paired human CRC tissues and statistical analysis was performed. *P < 0.05 vs. normal colonic tissues. e The negative correlation between RhoA and miR-133a-3p expression was detected by Spearman’s correlation analysis in human CRC tissues

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