Fig. 1

The effect of ATRA treatment on serous ovarian cancer cell proliferation. Cell survival in response to 6 days ATRA treatment (1, 5 μM) is shown in order of cell invasiveness a OVCAR-3, b OAW28, c COV-318, d COV- 362, e OV-90 and primary serous ovarian cancer cells (n = 6) (f). Data are expressed as percentage of control, mean ± SEM from 3 to 4 independent experiments (20–24 determinations) in (a-e) and quadruplicate determinations for primary cells from 6 individual patients in (f). Statistical significance for a-e was determined using one-way ANOVA (Tukey multiple comparison post hoc test) and the paired Friedman test (Dunn’s multiple comparison test) for (f), *p < 0.05