Fig. 1

miR-6875-3p expression was inversely associated with BTG2 expression in HCC tissues, and high miR-6875-3p expression predicted Shorter RFS and OS. a Analysis of miR-6875-3p expression in HCC tissues and tumor-adjacent tissues using ISH. b The expression levels of miR-6875-3p were detected by qRT-PCR in 108 paired HCC and tumor-adjacent tissues. c Analysis of BTG2 expression in HCC tissues and tumor-adjacent tissues via IHC. d Expression of miR-6875-3p was inversely correlated with the mRNA level of the BTG2 (R = − 0.2638, p < 0.01, Spearman’s correlation analysis). e, f Kaplan-Meier analysis suggested that the OS and RFS rates of the low miR-6875-3p expression group were higher than those of the high miR-6875-3p expression group (p < 0.05). Scale bars, 50 mm. Data are shown as the mean ± SD of three replicates (*p < 0.05)