Fig. 1

has-miR-506-3p regulated LHX2 expression and mediated the Wnt/β-catenin signaling pathway in NPC by microarray profiling. a-d heat maps with hierarchical clustering analysis on the microarray dataset GSE12425, GSE13597, GSE53819 and GSE64634 show differentially expressed genes. The abscissa represents the sample number, while the ordinate shows the gene name. The histogram of the upper right is a color order. The color change from top to bottom indicates that the expression of sample is from high to low. Each rectangle corresponds to the expression of sample, and each column represents the expression of all genes in each sample. The left dendrogram indicates the result of cluster analysis of different genes from different samples. The top bar represents the sample type, and the upper right box represents the color of the sample. The blue is the normal control sample, and the red is the tumor sample. e Venn diagrams of dataset GSE12425 (blue), GSE13597 (red), GSE53819 (green) and GSE64634 (yellow) show the number of differentially expressed genes. The middle part as the blue arrow shown represents the intersection of four datasets. f Venn diagrams of predicted miRNAs from the databases of TargetScan (blue), DIANA (red), miRDB (brown), microRNA.org (yellow) and mirDIP (green). The middle part as the blue arrow shown represents the intersection of f datasets