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Fig. 11 | Journal of Experimental & Clinical Cancer Research

Fig. 11

From: RETRACTED ARTICLE: MicroRNA-506 inhibits tumor growth and metastasis in nasopharyngeal carcinoma through the inactivation of the Wnt/β-catenin signaling pathway by down-regulating LHX2

Fig. 11

Up-regulation of miR-506 or silencing LHX2 suppressed LNM, and tumorigenicity in nude mice with NPC. a images of the lymph node metastatic sites in nude mice following intraperitoneal injection; b the number of tumor-bearing mice with LNM following intraperitoneal injection; c the number of LNM; d the fluorescence absorption value of tumor in each group; e tumor growth curves in each group; f pathological changes of xenograft tumor tissues detected by HE staining; * p < 0.05, vs. the blank and NC groups; LNM, lymph node metastasis; NC, negative control; miR-506, microRNA-506; NPC, nasopharyngeal carcinoma; LHX2, LIM Homeobox 2; E-cadherin, epithelial-cadherin; HE, hematoxylin-eosin; RT-qPCR, reverse transcription-quantitative polymerase chain reaction

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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