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Fig. 8 | Journal of Experimental & Clinical Cancer Research

Fig. 8

From: RETRACTED ARTICLE: MicroRNA-506 inhibits tumor growth and metastasis in nasopharyngeal carcinoma through the inactivation of the Wnt/β-catenin signaling pathway by down-regulating LHX2

Fig. 8

Up-regulation of miR-506 or silencing of LHX2 promoted NPC cell apoptosis. a the CNE2 cell apoptosis following transfection as determined by flow cytometry Annexin V/PI double parameter method; b the 5-8F cell apoptosis following transfection as evaluated by flow cytometry Annexin V/PI double parameter method; c the protein level of cleaved caspase-3 in CNE2 cells following transfection as determined by western blot analysis; d the protein level of cleaved caspase-3 in 5-8F cells following transfection as measured by western blot analysis; * p < 0.05, vs. the blank and NC groups; NC, negative control; miR-506, microRNA-506; NPC, nasopharyngeal carcinoma; PI, propidium iodide; LHX2, LIM Homeobox 2

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