Fig. 5

miR-29a robustly increases invasion in PTEN-competent and PTEN-deficient glioblastoma cells. a) Phase micrographs of invading LN229 or U251 glioblastoma cells in Matrigel invasion assay after exposure to control or miR-29a mimic (100 nM). Scale approximately 50 μm. b) Quantitation of data depicted in a). Data shown are mean ± SEM of 6 replicates. *P < 0.05 for LN229 and *P < 0.0001 for U251 glioblastoma cells. c) Phase micrographs of invading LN229 or U251 glioblastoma cells in Matrigel invasion assay after exposure to control or miR-29a inhibitor (100 nM). Scale approximately 50 μm. d) Quantitation of data depicted in c). Data shown are mean ± SEM of 6 replicates. *P < 0.01 for LN229 and *P < 0.0001 for U251 glioblastoma cells