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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery

Fig. 4

H-EV promoted A549 cell proliferation, survival ad mobility in a miR-12-5p-dependent manner. A549 or H23 cells were transfected with miR-12-5p inhibitor and treated with H-EV. a-k, cell functional assays were performed as described in Fig. 1. Non-treated A549 or H23 cells were used as negative control (NC). Bar in i indicates 20 μm. Data in h and j were presented as fold change comparing to NC. Tukey's test was used for statistical analysis. *, p < 0.05; **, p < 0.01; ***, p < 0.001

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