Fig. 2
Impact of ZNF326 expression on the proliferation and invasiveness of glioma cells in vitro. ZNF326 overexpression significantly enhanced the colony formation (a, b), invasiveness (e, f, magnification-400×), and proliferation (i, j) of U87 and U251 glioma cell lines. Conversely, ZNF326 knockdown significantly inhibited colony formation (c, d), invasiveness (g, h, magnification-400×), and proliferation (k, l) of U87 and U251 glioma cell lines. CTL: control group. Each experiment was performed in triplicate. Columns: mean numbers. Bars: S.D. (*: P < 0.05; **: P < 0.01; ***: P < 0.001)