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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Receptor tyrosine kinase-dependent PI3K activation is an escape mechanism to vertical suppression of the EGFR/RAS/MAPK pathway in KRAS-mutated human colorectal cancer cell lines

Fig. 4

Heterodimerization of RTK. Indirect immunofluorescence for EGFR (green) and HER2 (red) and their merge with DAPI in HCT116 vs HCT116 CM-R; z-stacking analysis reveals co-localization (yellow dots) of the two receptors on cell membranes at multiple focal planes electively in HCT116 CM-R cells

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