Fig. 8

Effect of FAT4 knockdown and overexpression on tumorigenesis in vivo. a Photographs of tumors excised from mice injected with normal cells or cells with modified FAT4 expression (n = 5 per group). After 56 days, the mice were sacrificed, and the tumors were weighed. b Tumor growth curves for mice injected with normal cells or cells with modified FAT4 expression. *P < 0.05, as determined by Student’s t-test