Fig. 4

PD-L1 is positively correlated with HAT1 in PDAC patient specimens. a, The mRNA levels of PD-L1 (CD274) and HAT1 as well as the corresponding heatmap of pancreatic cancer dataset reported by the QCMG group (n = 456) [26]. b, The GEPIA web tool was used to determine the correlation between the mRNA expression levels of PD-L1 and HAT1 in human pancreatic cancer samples. c, Images of the IHC analysis of PD-L1 and HAT1 using TMA (n = 41 PDAC) tissue sections. Scale bars are shown as indicated. d, Correlation analysis of the staining index for the expression of the HAT1 and PD-L1 proteins in PDAC patient specimens (n = 41). Pearson product-moment correlation coefficients and the P values are also shown