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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Cross-talk among AFAP1-AS1, ACVR1 and microRNA-384 regulates the stemness of pancreatic cancer cells and tumorigenicity in nude mice

Fig. 6

The mechanism of AFAP1-AS1 regulating PC cell stemness. High expression of AFAP1-AS1 was found in PC cells, while down-regulation of AFAP1-AS1 enhanced the expression of miR-384. While up-regulation of miR-384 inhibits the expression of ACVR1, which suppresses PC cell proliferation and invasion. AFAP1-AS1, actin filament-associated protein 1 antisense RNA 1; ACVR1, activin receptor A type I; PC, pancreatic cancer; miR-384, microRNA-384

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