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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway

Fig. 2

Long term TS-induced CSC-like properties were associated with IL-33 upregulation. Mice were exposed to TS for 12 weeks, and representative micrographs of liver tissues were stained with H&E (a). The expression of IL-33 was detected by immunohistochemical staining (b). c IL-33 positive areas in TS group relative to FA group. d Western blotting of IL-33 in liver tissues. β-actin was served as the loading control. e Six animal samples per group were used for the densitometric analysis of IL-33 protein. Data are expressed as mean ± SD. The significance was assessed with unpaired two-tailed Student’s t test. ## P < 0.01, compared with FA control. FA = filtered air; TS = tobacco smoke

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