Fig. 3
From: Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway
Long term TS exposure-induced CSC-like properties were related to p38 activation. Mice were exposed to TS for 12 weeks; Western blotting of p38 (a) and AP-1 proteins (c). Densitometric analyses of Western blotting for p-p-38/p-38 (b), p-c-Jun/c-Jun (d), JunD (e), p-c-Fos/c-Fos (f) and FosB (g) were measured after normalization to β-actin; six animal samples per group were used for the densitometric analysis. Data are expressed as mean ± SD. The significance was assessed with unpaired two-tailed Student’s t test. # P < 0.05, ## P < 0.01, compared with FA control. FA = filtered air; TS = tobacco smoke