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Table 1 The correlation between p53 mutational status and clinicopathologic features in 78 NSCLC patients

From: Cathepsin L activated by mutant p53 and Egr-1 promotes ionizing radiation-induced EMT in human NSCLC

Clinicopathological feature

p53

χ 2

P-value

WT (n = 35)

Mut (n = 43)

Gender

 

1.4110

0.2349

Male

19

29

  

Female

16

14

  

Age (years)

 

0.2276

0.6333

< 60

12

17

  

≥60

23

26

  

Histological type

 

4.2338

0.1165

SCC

8

17

  

ADC

27

26

  

Differentiation

 

3.8980

0.1424

well

5

4

  

Moderate

24

23

  

poor

6

16

  

Nodes metastasis

 

4.9079

0.0267*

N0

25

20

  

N1-3

10

23

  

Distant metastasis

 

–

0.1232

M0

35

39

  

M1

0

4

  

TNM stage

 

6.4440

0.0399*

I

16

15

  

II

7

12

  

III-IV

12

16

  
  1. P by χ 2 test, squamous cell carcinoma (SCC), adenocarcinoma (ADC)
  2. *P < 0.05 was considered significant