Skip to main content

Table 1 Association of FBXO22 Upregulation with Clinicopathologic Features in 110 Primary HCCs

From: FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

Features

Total

FBXO22 Expression

P value

Normal Expression

Over Expression

Sex

 Male

90

35

55

0.746

 Female

20

7

13

Age (years)

  ≤ 50

55

22

33

0.695

 >50

55

20

35

ALT

 <70

100

37

63

0.420

  ≥ 70

10

5

5

AST

 <70

96

37

59

0.839

  ≥ 70

14

5

9

Serum AFP (ng/ml)

 <400

56

29

27

0.003

  ≥ 400

54

13

41

Tumor size (cm) *

  ≤ 5

40

21

19

0.019

 >5

70

21

49

Tumor number

 Single

84

31

53

0.620

 Multiple

26

11

15

BCLC stage

 0 + A

70

31

39

0.140

 B + C

40

12

28

TNM stage

 I + II

81

34

47

0.171

 III + IV

29

8

21

Differentiation

 Well/moderate

71

27

44

0.964

 Poor

39

15

24

Vascular invasion

 Yes

88

38

50

0.031

 No

22

4

18

Tumor capsule

 Absent

53

16

37

0.096

 Present

57

26

31

Recurrence

 Yes

53

24

29

0.139

 No

57

18

39

  1. NOTE. Statistical significance (P < 0.05) is shown in bold
  2. * Tumor size was measured by the length of the largest tumor nodule
Back to article page

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us