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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

Fig. 3

The systemic delivery of miR-34a. Nanoparticles which encapsulating with miR-34a are delivered into blood vessel intravenously. These nanocarriers overcome barriers from organs, tissues and cells to reach at target cells and release miR-34a mimics under specific intracellular environment. Then miR-34a binds with 3’-UTR of target mRNA, resulting in the degradation of mRNA or the inhibition of translation

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