Fig. 1
From: DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53
Expression of DRAM2 in non-small cell lung cancer (NSCLC). a. DRAM2 protein expression analyzed by immunohistochemistry in (a) alveolar and (b) normal bronchial epithelial cells; (c) squamous cell carcinoma and (d) adenocarcinoma. Magnification, × 200. b. Relative expression of DRAM2 mRNA in 20 pairs of NSCLC samples and adjacent normal lung tissues.DRAM2 overexpressed in NSCLC samples and have statistical significance,p = 0.0466. c. Western blot showing the detection of DRAM2 and p53 in the lysates of 15 paired tumor (C) and adjacent normal tissues (N). β-actin was used as a loading control. The results were quantified using ImageLab, and intensity values were normalized to the β-actin band.The relative expression was quantified below