Fig. 5
From: DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53
Expression of p53 and DRAM2 were restrained by each other. a Protein p53 and its target, p21, were detected in the context of DRAM2 overexpression and downregulation in SK and A549 cells, respectively. The gray level of the proteins were detected, the corresponding p value were provided at the top of the graphs and those changed proteins were marked.*p < 0.05, **p < 0.01, ***p < 0.001. b Protein DRAM2 was decreased after TP53 was transfected into A549 and H1299 cells. The gray level of the proteins were detected, the corresponding p value were provided at the top of the graphs and those changed proteins were marked.*p < 0.05, **p < 0.01, ***p < 0.001