Fig. 6
From: DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53
Overexpression of p53 restrained the effects of DRAM2 on cell migration and proliferation. a. MTT assay; b. Colony formation assay; c. Transwell migration were performed in the context of DRAM2 overexpression and downregulation in H661 cells. Only colony formation assay for both downregulated p53 and DRAM2 have statistical significance,p = 0.0482. d. Effects of DRAM2 levels on the expression of proteins associated with cell proliferation, migration, and p53 in transfected H661 cells