Fig. 1

Circ_0000190 is down-regulated in MM tissues and peripheral blood. a Divergent primers detected circular RNAs in cDNA but not gDNA. b RT-PCR analysis of circ_0000190 in human MM and normal healthy tissues. Tumor vs. Normal, P < 0.001. c qRT-PCR analysis of circ_0000190 in human MM and normal healthy peripheral blood. Tumor vs. Normal, P < 0.001. d Progression-freecurve analysis of high or low expression of circ_0000190 in MM patients. e Overall survival curve analysis of high or low expression of circ_0000190 in MM patients