Fig. 7
Circ_0000190/miR-767-5p/MAPK4 axis on the cell progression of MM. a Luciferase reporter assay of circ_0000190/miR-767-5p/MAPK4 axis. b The CCK8 assay detects the effect of circ_0000190 and sh- circ_0000190, miR-767-5p mimics and inhibitor, MAPK4 and shMAPK4 on cell viability of H929 cells. c The CCK8 assay detects the effect of circ_0000190 and sh-circ_0000190, miR-767-5p mimics and inhibitor, MAPK4 and shMAPK4 on cell viability of MM. 1S cells. d EdU labeling assay detects the effect of circ_0000190 and sh- circ_0000190, miR-767-5p mimics and inhibitor, MAPK4 and shMAPK4 on cell proliferation. e Flow cytometry detects the effect of circ_0000190 and sh-circ_0000190, miR-767-5p mimics and inhibitor, MAPK4 and shMAPK4 on cell cycle. f Western blot analysis detects the effect of circ_0000190 and sh-circ_0000190, miR-767-5p mimics and inhibitor, MAPK4 and shMAPK4 on the expression of MAPK4, CDK6, CDK4, Cyclin D1 and Cyclin E, p21Cip1. Different letters in the figure indicate statistically significant differences (P < 0.05)