Fig. 7

The stable expressing cells were used for tumor xenografts study in vivo. a The nude mice sample tumor from respective group was shown. b Tumor growth curves in nude mice were shown. Tumor volume was calculated every five days after injection and tumor was excised after 45 days; data are presented as mean ± SD (n = 8, each group). ^**P < 0.01 vs. ZRANB2(−)-NC + SNHG20(−)-NC group, ^##P < 0.01 vs. ZRANB2(−) group, ^&&P < 0.01 vs. SNHG20(−) group. c The survival curves of nude mice that were injected into the right striatum were shown (n = 8, each group). d CD34-PAS staining was used to detect the VM in xenografted tumor; data are presented as mean ± SD (n = 5, each group). ^*P < 0.05 vs. ZRANB2(−)-NC + SNHG20(−)-NC group, ^**P < 0.01 vs. ZRANB2(−)-NC + SNHG20(−)-NC group, ^##P < 0.01 vs. ZRANB2(−) group, ^&&P < 0.01 vs. SNHG20(−) group. Scale bars indicate 25 μm