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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: MicroRNA-7 as a potential therapeutic target for aberrant NF-κB-driven distant metastasis of gastric cancer

Fig. 2

Low miR-7 and high RelA/p65 expression are correlated with poor prognosis of GC patients. The correlations between miR-7, RelA/p65 and multiply survival rates were determined by Kaplan-Meier analysis from TCGA STAD database. a miR-7 downregulation is related to shorter overall survival (OS) (n = 593, P = 0.0012, left panel). High RelA/p65 indicated poor OS (n = 876, P = 5.5e-06, right panel). b Low miR-7 indicated shorter fist-progression survival (FPS) (n = 359, P = 0.00016, left panel). High RelA/p65 indicated worse FPS (n = 641, P = 0.00098, right panel) according to TCGA cohort. c Low miR-7 indicated poor post-progression survival (PPS) (n = 222, P = 0.049, left panel). High RelA/p65 indicated shorter PPS (n = 499, P = 9.2e-09, right panel). d Low miR-7 is correlated with shorter progression-free survival (PFS) (n = 222, P = 0.049, left panel). High RelA/p65 indicated poor PFS (n = 499, P = 9.2e-09, right panel). e Low miR-7 is correlated with worse distant metastasis-free survival (DMFS) (n = 192, P = 0.0039, left panel). High RelA/p65 indicated shorter DMFS (n = 444, P = 3e-05, right panel). P values were determined by log-rank test

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