Fig. 5From: Histone deacetylase inhibitors suppress aggressiveness of head and neck squamous cell carcinoma via histone acetylation-independent blockade of the EGFR-Arf1 axisPhospho-EGFR binds to Arf1 in HNSCC cells. a The EGFR-Arf1 binding in HN12 cells determined by IP. Preimmune IgG was used as a negative control. b The effect of erlotinib on Arf1 activation determined by Western blotting. c The effect of 5 μM erlotinib on the engagement of Arf1 in the EGFR immunocomplex determined by IPBack to article page