Fig. 1
H2S deficiency increased the expression and activity of IDO1 in Cse−/− mice. a HPLC analysis of Kyn/Trp ratios in wild-type (wt) mice and Cse−/− mice, N = 6. b, c Analysis of IDO1 expression in different tissues of wt mice and Cse−/− mice. Total RNA and protein were extracted from different tissues of wt mice and Cse−/− mice. mRNA expression of Ido1 was analyzed by qPCR, values from three independent experiments are presented as the mean ± SEM, *p < 0.05, **p < 0.01, Student’s t test. Protein expression of IDO1 was analyzed by western blot