Fig. 7

H2S exhibited immunotherapeutic efficacy in H22 HCC-bearing mice by inducing T-effector cells and inhibiting MDSCs. a Representative immunostaining images of IDO1 protein (× 400 magnification) and CD8+ T cells (× 400 magnification) and MDSC cells from each experimental group (× 400 magnification). b-d Quantification of IDO1 positive cells, CD8+ T cells and MDSC cells in each group. L-1-MT group, N = 4, other groups, N = 9. Statistical significance was determined by one-way ANOVA followed by Dunnett’s test. *P < 0.05, **P < 0.01, bars show the group mean ± SD