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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: CCDC6 and USP7 expression levels suggest novel treatment options in high-grade urothelial bladder cancer

Fig. 6

a Left: Representative images of G3 and G1 primary samples stained for CCDC6 and USP7 at immunohistochemistry. CCDC6 staining was revealed by DAB-conjugated secondary antibody, USP7 immunoreaction was revealed by Fast Red. The images show a high grade of concordance between CCDC6 and USP7 expression levels. Magnification, 40X. Right: K.mean cluster analysis showed two specific aggregations (cluster 1 and 3) with high prevalence of G3 tumor samples, showing two different patterns of biomarkers staining, and a third cluster (cluster 2) with an equal distribution between G1 and G3 tumors are shown. b CCDC6 e USP7 expression levels may suggest novel therapeutic scheme of personalized treatment in urothelial carcinoma

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