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Table 1 Prognostic value of different risk factors

From: LRG-1 promotes pancreatic cancer growth and metastasis via modulation of the EGFR/p38 signaling

Risk factors Univariate regression analysis Multivariate regression analysis Overall survival
  HR 95% CI P value HR 95% CI P value Mean ± SD, months P value
LRG-1 expression
 Group 1: Low 2.29 1.47–3.57 <0.001 2.30 1.43–3.71 0.001 28.66 ± 1.73 <0.001
 Group 2: High 18.13 ± 1.40
Tumor stage
 Group 1: Stage I 3.02 1.97–4.62 <0.001 2.48 1.59–3.87 <0.001 32.08 ± 2.53 <0.001
 Group 2: Stage II 22.41 ± 1.37
 Group 3: Stage III 10.08 ± 1.24
R1 resection
 Group 1: Yes 2.87 1.23–6.66 0.015 2.16 0.89–5.25 0.089 12.50 ± 2.48 0.009
 Group 2: No 24.88 ± 1.36
Carbohydrate antigen 125
 Group 1: <35 2.04 1.25–3.32 0.004 1.39 0.82–2.34 0.219 26.06 ± 1.51 0.003
 Group 2: ≥35 16.91 ± 2.06
Carbohydrate antigen 19–9
 Group 1: <37 1.68 1.26–2.24 <0.001 1.42 1.06–1.90 0.020 31.01 ± 2.67 0.001
 Group 2: 37–200 23.78 ± 1.55
 Group 3: >200 18.00 ± 1.89