Fig. 2

LPCAT1 was upregulated in various cancer patients, especially in lung cancer. a The copy number of LPCAT1 was directly proportional to the amount of mRNA expressed in the TCGA database. Blue and red circles represent non-mutated and missense genes, respectively. b LPCAT1 expression levels in normal lung tissues (left, n = 350) and LUAD tissues (right, n = 254) based on TCGA data. Statistical analysis (One-way ANOVA). c The expression of LPCAT1 in LUAD (left) was significantly higher than in LUSC (right) based on TCGA data. Black, blue and red circles represent not sequenced, no mutation and missense genes, respectively. d Analysis of the THPA database showed that the LPCAT1 expression was relatively higher in patients with primary lung cancer than in those with other 16 tumors. e The positive rate of LPCAT1 was up to 80% in lung cancer tissues based on the THPA database. f, g The expression of LPCAT1 in NSCLC cell lines was detected by PCR and Western blotting. Data are expressed as mean ± SD, *P < 0.05, **P < 0.01, one-way ANOVA