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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Landscape of tumor suppressor long noncoding RNAs in breast cancer

Fig. 1

Discovery and validation of the TSLNR landscape in breast cancer. a Hierarchical clustering of the genes differentially expressed in breast cancer relative to normal tissue in the HMUCC cohort (N = 33) (FC > 1.5, P < 0.05). b Hierarchical clustering of the genes differentially expressed in breast cancer relative to normal tissue in the TCGA cohort (N = 1105) (FC > 1.5, P < 0.05). The red to blue color gradient indicates high to low expression levels, respectively. c Overlapping lncRNAs with downregulated expression in the HMUCC and TCGA breast cancer cohorts identified via Venny online software analysis (http://bioinfogp.cnb.csic.es/tools/venny/). d TSLNRs validated in the TCGA breast cancer cohort (FC > 1.5, P < 0.001). ****P < 0. 0001; **P < 0. 01; *P < 0.05; NS: no significance

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