Fig. 6From: SHP1 and SHP2 inhibition enhances the pro-differentiative effect of phorbol esters: an alternative approach against acute myeloid leukemiaTreatment with prostratin and NSC87877 augments survival in an in vivo leukemia mouse model. a) Box plots showing the survival distribution of the animals treated with PRS, NSC and their combination. b) Kaplan-Meier plots showing the survival curves for immunodeficient mice transplanted with HL-60 cells and treated with PRS, NSC and their combination. Comparisons were made against control (vehicle) groupBack to article page