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Table 1 Clinical features of patient samples used in the present study

From: SHP1 and SHP2 inhibition enhances the pro-differentiative effect of phorbol esters: an alternative approach against acute myeloid leukemia

ID

Age (years)

FAB subtype

Karyotype

Mutations

AML1

53

M0

46, XX, t(3;3)(q21;q21) [20]

WT1

IDH1

AML2

59

M0

46, XY

N/D

AML3

57

M0

46, XY

N/A

AML4

52

M1

45, XX, −7 [15]

N/D

AML5

71

M0

46, XX, del (5q)(q13q35) [13]

47, XXSL, + 8 [2]

N/A

AML6

39

M4

46, XY

FLT3

AML7

50

Secondary AML

No metaphases

N/D

AML8

64

M5

No metaphases

NPM1

  1. Legend: N/A: not available, N/D: not detected, FAB: French-American-British classification