From: SHP1 and SHP2 inhibition enhances the pro-differentiative effect of phorbol esters: an alternative approach against acute myeloid leukemia
ID
Age (years)
FAB subtype
Karyotype
Mutations
AML1
53
M0
46, XX, t(3;3)(q21;q21) [20]
WT1
IDH1
AML2
59
46, XY
N/D
AML3
57
N/A
AML4
52
M1
45, XX, −7 [15]
AML5
71
46, XX, del (5q)(q13q35) [13]
47, XXSL, + 8 [2]
AML6
39
M4
FLT3
AML7
50
Secondary AML
No metaphases
AML8
64
M5
NPM1