Fig. 4From: Wild type p53 function in p53Y220C mutant harboring cells by treatment with Ashwagandha derived anticancer withanolides: bioinformatics and experimental evidenceInteractions of Wi-A with p53Y220C near Cys 220. a Binding pose of Wi-A within the binding site near Cys 220 b 2D representation of the interactions of Wi-A with p53Y220C. Interactions of Wi-N with p53Y220C protein structure. c Binding pose of Wi-N within the binding cavity of p53Y220C near Cys 220 d 2D representation of the interactions of Wi-N with surrounding residues within the cavity of p53Y220C. Charge complementarity of Wi-A and Wi-N with the binding cavity. Wi-A e and Wi-N f both were fitting inside the cavity according to the charge distribution within it. White region represents the hydrophobic region whereas blue and red represents the hydrophilic regionBack to article page