Skip to main content
Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Long non-coding RNA LINC00968 attenuates drug resistance of breast cancer cells through inhibiting the Wnt2/β-catenin signaling pathway by regulating WNT2

Fig. 3

Overexpressed LINC00968 or silenced WNT2 contributes to reduced drug resistance of breast cancer cells. a drug resistance of transfected MCF-7/ADM cells to ADR as evaluated by CCK-8 assay. b drug resistance of transfected MCF-7/ADM cells to Taxel as determined by CCK-8 assay. c drug resistance of transfected MCF-7/ADM cells to VCR as assessed by CCK-8 assay. d protein bands of MRP1, BCRP, and P-gp in transfected MCF-7/ADM cells ad determined by Western blot analysis. e histogram of MRP1, BCRP, and P-gp protein levels in each group. f drug resistance of transfected KPL-4/ADM cells to ADR as evaluated by CCK-8 assay. g drug resistance of transfected KPL-4/ADM cells to Taxel as determined by CCK-8 assay. h drug resistance of transfected KPL-4/ADM cells to VCR as assessed by CCK-8 assay. i protein bands of MRP1, BCRP, and P-gp in transfected KPL-4/ADM cells ad determined by Western blot analysis. j histogram of MRP1, BCRP, and P-gp protein levels in each group. *p < 0.05 vs. the control group; #p < 0.05 vs. the blank and NC groups; &p < 0.05 vs. the LINC00968 vector + WNT2 vector group

Back to article page