Fig. 1

Differential expression of fascin-1 (FSCN1) and miR-200b in bladder cancer (BLCA) tissues and cells. a and b Kaplan–Meier analysis of overall survival based on FSCN1 (a) and miR-200b (b) expression levels in patients with BLCA from the TCGA database. Patients with BLCA were divided into FSCN1 (or miR-200b) high expression group (33% of the total, with the highest FSCN1 (or miR-200b) expression) and low expression group (33%, with the lowest FSCN1 (or miR-200b) expression). c and d The mRNA level of FSCN1 (c) and miR-200b (d) in 23 normal bladder tissues and 60 BLCA tissues was measured by qPCR. Data were analyzed by Mann-Whitney U test. e Correlation between FSCN1 and miR-200b of 60 BLCA tissues. Data were analyzed by Spearman correlation analysis. f and g The mRNA level of FSCN1 (f) and miR-200b (g) in BLCA cell lines was measured by quantitative PCR (qPCR) and normalized by RT4 cell line. Data were analyzed by T-test. Data are presented as the mean ± standard deviation (SD). *P < 0.05; **P < 0.01; ***P < 0.001; ns, not significant