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Table 3 Univariate and multivariate analysisa of clinicopathological parameters in association with overall survivalb

From: HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3

Variable

Univariable analysis

Multivariate analysis

HR

95% CI

p value

HR

95% CI

p value

Age

0.82

0.54–1.25

0.352

     

Histological subtype

0.82

0.50–1.35

0.44

     

Grade

2.02

1.19–3.41

0.009

*

1.88

1.13–3.13

0.015

*

FIGO stage

2.63

1.29–5.34

0.008

*

2.27

1.16–4.46

0.017

*

Lymph node metastasis

1.92

1.19–3.10

0.008

*

1.95

1.20–3.15

0.007

*

Serum CA125

0.98

0.62–1.55

0.925

     

Ascites

0.70

0.45–1.08

0.11

     

HOXD-AS1 expression

1.94

1.22–3.06

0.005

*

1.92

1.23–3.00

0.004

*

  1. aCox hazard model
  2. b200 patients with full clinical information including age, FIGO stage,histological type,type of chemotherapy and type of surgery.HR,hazard ratio;CI,confidence interval;FIGO, International Federation of Gynecology and Obstetrics; CA125, carbohydrate antigen 125; HOXD-AS1, HOXD Cluster Antisense RNA 1
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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