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Table 1 Expression of WISP2 in ESCC and the relationship with clinicopathological parameters.

From: WISP2 exhibits its potential antitumor activity via targeting ERK and E-cadherin pathways in esophageal cancer cells

Parameter cases WISP2 χ2 P
+ Positive(%)
Gender
 Male 121 44 77 36.36   
 Female 95 33 62 34.74 0.06 0.89
Age(years)
  ≤ 60 86 35 51 40.70   
 >60 130 42 88 32.31 0.21 0.25
Tumor grade
 I 50 20 30 40.00   
 II 78 29 49 37.18
 III 88 28 60 31.82 1.78 0.62
Infiltration depth
 Under serous layer 99 71 28 71.72   
 Serous layer 117 6 111 0.51 103.65 < 0.01
Lymph node metastasis
 Yes 112 2 110 1.79   
 No 104 75 29 72.12 116.27 < 0.01
TNM stages
 I,II stages 88 71 17 80.68   
 III,IV stages 128 6 122 4.69 131.28 < 0.01
Diameter(cm)
 <4 97 36 61 37.11   
  ≥ 4 119 41 78 34.45 0.69 0.78
General type
 Ulcerative type 67 21 46 23.8   
 Medullary type 97 34 63 23.8   
 Mushroom type 41 18 23 18.2   
 Constrictive type 11 4 7 25.0 0.33 0.96
Location
 Top 28 14 14 50.00   
 Middle 116 34 82 29.31   
 Bottom 72 29 43 40.28 5.22 0.07