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Table 1 Expression of WISP2 in ESCC and the relationship with clinicopathological parameters.

From: WISP2 exhibits its potential antitumor activity via targeting ERK and E-cadherin pathways in esophageal cancer cells

Parameter

cases

WISP2

χ2

P

+

Positive(%)

Gender

 Male

121

44

77

36.36

  

 Female

95

33

62

34.74

0.06

0.89

Age(years)

  ≤ 60

86

35

51

40.70

  

 >60

130

42

88

32.31

0.21

0.25

Tumor grade

 I

50

20

30

40.00

  

 II

78

29

49

37.18

 III

88

28

60

31.82

1.78

0.62

Infiltration depth

 Under serous layer

99

71

28

71.72

  

 Serous layer

117

6

111

0.51

103.65

< 0.01

Lymph node metastasis

 Yes

112

2

110

1.79

  

 No

104

75

29

72.12

116.27

< 0.01

TNM stages

 I,II stages

88

71

17

80.68

  

 III,IV stages

128

6

122

4.69

131.28

< 0.01

Diameter(cm)

 <4

97

36

61

37.11

  

  ≥ 4

119

41

78

34.45

0.69

0.78

General type

 Ulcerative type

67

21

46

23.8

  

 Medullary type

97

34

63

23.8

  

 Mushroom type

41

18

23

18.2

  

 Constrictive type

11

4

7

25.0

0.33

0.96

Location

 Top

28

14

14

50.00

  

 Middle

116

34

82

29.31

  

 Bottom

72

29

43

40.28

5.22

0.07