Fig. 2

Zoledronic acid inhibits the proliferation of cervical cancer cells derived CSCs in vitro. Parental HeLa, SiHa, and CaSki cells as well as their derived CSCs were seeded in 96-well plates and treated with zoledronic acid at different concentrations for 1–5 days. Cell viability was determined by the modified MTT assay. OD values of each treated group were compared with that of the control at the same time point. Control vs. 5, 10, 20, 40, and 80 μM of zoledronic acid: * P < 0.05, ** P < 0.01. Results are shown as mean values ± SD of independent experiments performed in triplicate