Fig. 3

Transcriptome analysis for RBMS3. a Volcano plot represented the distribution of mapped transcripts. b Enrichment analysis of the KEGG pathway. The size and color of the dots represented the number of enriched genes and the adjusted P values, respectively. c, d Gene Set Enrichment Analysis (GSEA) was used to analyze the distribution of differentially expressed genes in WNT and MYC pathways. e Heat map represented the down-regulated and upregulated genes measured in SUM-1315 cells. R1, R2, R3 and V1, V2 and V3 represented RBMS3-overexpressed group and the control group, respectively. The red arrow indicated that Twist1 was downregulated in the RBMS3-overexpressed group