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Table 1 Correlation between RNF38 and clinicopathological characteristics in 200 HCC patients

From: Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma

Variables Number of patients  
  RNF38 high RNF38low P value
Gender
 Female 12 15 0.611
 Male 86 87  
Year
  < 52 43 53 0.253
  ≥ 52 55 49  
Hepatic cirrhosis
 Yes 87 91 0.921
 No 11 11  
HbsAg
 Positive 79 86 0.491
 Negtive 19 16  
HCV
 Positive 0 2 0.498a
 Negtive 98 100  
AFP
  < 20 33 43 0.217
  ≥ 20 65 59  
Tumor size (cm)
  < 5 46 67 0.008 (**)
  ≥ 5 52 35  
Tumor number
 Single 83 85 0.793
 Multiple 15 17  
Tumor encapsulation
 Complete 61 43 0.004 (**)
 None 37 59  
Tumor differentiation
 I + II 66 79 0.110
 III + IV 32 23  
Edmondson-Steiner Grade
 I + II 58 62 0.817
 III 40 40  
Embolus
 Absence 60 77 0.030 (*)
 Present 38 25  
TNM stage
 I 61 79 0.019 (*)
 II + III 37 23  
  1. Note: a, Fisher test; AFP, alpha-fetoprotein; p < 0.05 was considered significant; **p < 0.01; *p < 0.05