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Table 1 Correlation between RNF38 and clinicopathological characteristics in 200 HCC patients

From: Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma

Variables

Number of patients

 
 

RNF38 high

RNF38low

P value

Gender

 Female

12

15

0.611

 Male

86

87

 

Year

  < 52

43

53

0.253

  ≥ 52

55

49

 

Hepatic cirrhosis

 Yes

87

91

0.921

 No

11

11

 

HbsAg

 Positive

79

86

0.491

 Negtive

19

16

 

HCV

 Positive

0

2

0.498a

 Negtive

98

100

 

AFP

  < 20

33

43

0.217

  ≥ 20

65

59

 

Tumor size (cm)

  < 5

46

67

0.008 (**)

  ≥ 5

52

35

 

Tumor number

 Single

83

85

0.793

 Multiple

15

17

 

Tumor encapsulation

 Complete

61

43

0.004 (**)

 None

37

59

 

Tumor differentiation

 I + II

66

79

0.110

 III + IV

32

23

 

Edmondson-Steiner Grade

 I + II

58

62

0.817

 III

40

40

 

Embolus

 Absence

60

77

0.030 (*)

 Present

38

25

 

TNM stage

 I

61

79

0.019 (*)

 II + III

37

23

 
  1. Note: a, Fisher test; AFP, alpha-fetoprotein; p < 0.05 was considered significant; **p < 0.01; *p < 0.05
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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