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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Cysteine-rich intestinal protein 1 suppresses apoptosis and chemosensitivity to 5-fluorouracil in colorectal cancer through ubiquitin-mediated Fas degradation

Fig. 4

CRIP1 inhibits Fas induced apoptosis of CRC cells. a. Western blot analysis of apoptotic related proteins in CRIP1 overexpressed or silencing indicated cells. b. Western blot analysis of the effects of CRIP1 on Fas-mediated apoptosis. c. CCK8 assay shows the effects of CRIP1 on Fas-mediated apoptosis. d. Annexin V-FITC/PI flow cytometry assay showed the effects of CRIP1 on Fas-mediated apoptosis. Bars on the upper panel represent percentage of cells in Q2 + Q4. e. TUNEL assay showed the effects of CRIP1 on Fas-mediated apoptosis of CRC cells. Bars on the right panel represent the percentage of TUNEL positive cells

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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