Fig. 1
From: Cell communication and signaling: how to turn bad language into positive one
The utility of miRNAs in diagnosis and therapy. miRNAs can be harvested from biological fluids and used as liquid biopsies, in which free circulating miRNAs or exosomal miRNAs can be captured and analyzed ex vivo (a). They have proved useful biomarkers for diagnosis, prognosis, personalized therapies or disease monitoring. miRNAs can also be employed as therapeutics or therapeutic targets: miRNA mimics can be used for replacement therapies by the use of delivery systems while miRNA inhibitors, such as locked nucleic acid-antisense oligonucleotides, for inhibition approaches (b)