Fig. 6

FOXL1 was a direct target gene of miR-301a-5p. a-c. The expression of FOXL1 and miR-301a-5p is negatively correlated in HCC cells with western blot and qRT-PCR. d The binding region between miR-301a-5p and FOXL1; e Luciferase reporter assay for confirmation of direct binding relationship between FOXL1 and miR-301a-5p was performed with luciferase reporter plasmids of wild type FOXL1 and mutant FOXL1