Fig. 2

TKT Enhanced the Proliferation, Migration, Invasion and Colony Formation of HCC Cells in vitro. a Protein levels of TKT in different HCC stable cell lines were evaluated by western blot. b Proliferation assays showed that knocking down TKT suppressed and overexpressing TKT enhanced the proliferation of HCC cells. c Cell cycle assay showed that TKT promoted the DNA synthesis and the transition from G0/G1 to S phase in HCC cells. d Wound-healing assays showed that knocking down TKT suppressed and overexpressing TKT enhanced the migration of HCC cells. e Transwell assay with Matrigel showing that knocking down TKT suppressed invasion of HCC cells. f Overexpressing TKT enhanced the colony formation of HCC cells (*: p < 0.05; **: p < 0.01)